KMID : 0984920080100020007
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Journal of Skin Barrier Research 2008 Volume.10 No. 2 p.7 ~ p.18
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Stratum corneun decontamination: Overview & clinical perspective
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Chan Heidi P.
Zhai Hongbo Maibach Howard I.
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Abstract
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The stratum corneum(SC), being the outermost layer of the skin and constantly exposed to the environment, is always at risk for contamination. SC decontamination models & methods and their implications as well as variables influencing the effectiveness of decontamination such as timing of decontamination and chemical nature of decontaminating solutions are analyzed. These models offer promise of an enhanced understanding of mechanisms involved and development of more effective interventions.
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KEYWORD
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skin decontamination, percutaneous penetration, percutaneous absorption, wash-in effect, sebum, tape stripping
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